As stated by Sacks, F. The DASH diet and the control diet at the lower salt levels were both successful in lowering blood pressure, but the largest reductions in blood pressure were obtained by eating a combination of these two i. The hypertensive subjects experienced an average reduction of From Wikipedia, the free encyclopedia.
This article needs more medical references for verification or relies too heavily on primary sources. Please review the contents of the article and add the appropriate references if you can. Unsourced or poorly sourced material may be challenged and removed. Department of Agriculture and U. Department of Health and Human Services Retrieved December 15, Department of Health and Human Services. News Reveals Best Diets Rankings for ". The New England Journal of Medicine.
A meta-analysis of individual data for one million adults in 61 prospective studies". Southern California Urology Institute.
Retrieved 21 April From Clinical Trial to Dinner Table". Cleveland Clinic Journal of Medicine. The Cleveland Clinic Foundation. National Heart, Lung, and Blood Institute. Human nutritions and healthy diets. Omnivore Entomophagy Pescetarian Plant-based. Bodybuilding supplements Meal replacement Therapeutic food. Certainly, you will lose weight if you reduce the calories you eat. But will you be healthier, will you be stronger, vibrant, and full of energy? I have seen many people who lose weight and they feel so energy-depleted they can barely walk some times.
So, they resume their previous eating patterns and gain all the weight back, and some more. Nutrisystem's doctors and dietitians have designed the program's meal plan in such a way that you get the most nutrients for the lowest possible amount of calories. This doesn't mean that you get to eat nuts, oatmeal and dry chicken. The food is not "too healthy" by any means. You get to enjoy regular-type food, like burgers, pizza, past, and chocolate, which has been specifically made to contain all the necessary nutrients without the salt, fats, and sugars that fast food or regular grocery food often contains.
Nutrisystem food items naturally have or are fortified with lean protein, healthy fats, and "slow release" low glycemic index complex carbs. Both companies were founded more than a decade ago to address high failure rates of clinical trials of psychotropic drugs, the efficacy of which are measured with subjective ratings susceptible to biases, variability and error.
MedAvante pioneered Central Ratings, an unconventional solution built on the novel idea of having a small highly calibrated cohort of expert raters administer clinical outcome assessments remotely. ProPhase became a global provider of measurement-related specialty solutions in clinical trials by focusing on optimizing the selection, use, and analysis of behavioral endpoints to mitigate trial risk and maximize the likelihood of study success.
As Central Ratings gained acceptance in large global studies, MedAvante replaced the paper-based rating scales its own clinicians were using by developing a digital platform to administer clinical outcome assessments eCOA and manage electronic source eSource data, starting in MedAvante-ProPhase is committed to continuing to bring digital innovation and scientific quality to the crucially important process of collecting, managing and analyzing clinical trial data.
Litwin was named to his current position in April Before assuming his current role, Dr. Litwin was President of Litwin Consulting LLC and he also co-developed and launched Patient Genesis, an innovative software platform used by health care providers to create, share and transfer knowledge to patients during the informed consent process.
For more than 14 years, Dr. He served for more than three years as CEO of ERT, leading the then public company in a private equity acquisition via leveraged buyout in Earlier in his career, Dr. Litwin earned his M.
Steve Herne, an experienced sales and business development executive in both technology and services, joined MedAvante-Prophase as Chief Commercial Officer in July with overall responsibility for sales and marketing. Prior to his appointment, he was Chief Commercial Officer, eHealth Solutions at Bioclinica, a provider of clinical trial management solutions. Herne began his career as a Senior Research Scientist for Inveresk Research before moving to a business development position at Quintiles and then returned to Inveresk as Senior Business Development Manager.
In that position, he led the planning and implementation of a finance reorganization process. Downing also lent support to responsibility, strategy, capital investment, expansion and financial training. In addition, he led a team responsible for the overall financial health of projects, including profitability, revenue recognition, cash flow, invoicing, and financial training for project managers and their teams.
Before joining Covance, Mr. Greg Barrett leads worldwide software and platform development for MedAvante-ProPhase, supporting clinical science and signal detection capabilities.
He joined the company in April , bringing 30 years of information technology experience. In his role as Global IT Leader for Covance, he oversaw team members supporting five business units with applications, architecture, business engagement and computer systems validation.
As Vice President of Regulatory and Quality Assurance since she has been responsible for evaluating activities of regulatory significance and ensuring that quality standards and regulatory requirements are implemented and maintained throughout the organization while leading audit teams in successful completion of more than 60 customer audits without a single significant finding.
Widely recognized for her achievements in organizational leadership, Ms. Wilmer is often sought for advice and collaboration and asked to share her expertise with professionals worldwide through networking and consulting.
Wilmer worked for more than 20 years in health care where she developed expertise in regulation interpretation. At Horizon Blue Cross Blue Shield of New Jersey, she successfully developed and managed health care policies and administrative procedures to ensure compliance with regulatory agencies and other standards for a network of over 10, providers.
She has developed recruitment, contracting, and retention strategies for employees, physicians, and ancillary providers. He also has a strong background and interest in psychometrics and neurocognitive assessment, having worked for over 20 years as a consultant on test development, including the revisions of the Wechsler intelligence and memory scales. Randolph is Clinical Professor of Neurology and Director of the Neuropsychology service at Loyola University Medical Center and is board-certified in clinical neuropsychology.
Before joining MedAvante-ProPhase in July , he held the position External Clinical Innovation Leader at Roche, where he was responsible for developing, integrating and operationalizing strategic innovations throughout drug development. Prior to that post, he was Vice President, Project Management, Americas for the clinical research organization PRA HealthSciences, leading a team of clinical research professionals covering all therapeutic areas.
He also held senior project management and operations posts at Worldwide Clinical Trials, Inc. Cioffi holds the B. Detke is a psychiatrist with more than 20 years of research experience and extensive clinical and drug development expertise.
This role included registration and regulatory commitment trials for Cymbalta, including major depressive disorder, diabetic peripheral neuropathic pain, generalized anxiety disorder, fibromyalgia and chronic pain, as well as pediatric trials. Detke teaches and supervises medical students and residents as Clinical Professor of Psychiatry at Indiana University School of Medicine. He trained in medicine and psychiatry at Harvard Medical School and at the Mt. Detke has published more than 60 manuscripts in peer-reviewed journals since Williams has more than 30 years of clinical research experience in both industry and academia.
She is now Professor Emerita at Columbia University. Williams is well known in the field for her development of psychiatric classifications and instruments to measure psychopathology. She is the author of more than scholarly publications and serves on the editorial boards of several psychiatric and social work journals. She has received numerous awards for her achievements and contributions in social work and psychiatry.
His research groups also led development programs for the analgesic drug tapentadol, the long-acting antipsychotic agent paliperidone palmitate, and other potential treatments for CNS disorders.
Kobak is a psychologist with more than 30 years of clinical research experience in both industry and university medical settings. Throughout his career, he has focused on clinical assessment, rater training, rating scale development and clinical trials methodology. Kobak founded the consultancy Research Training Associates, where he developed new methodologies for training and calibrating raters in clinical trials using digital technologies.
Kobak managed a clinical trials unit and pioneered the use of computer-administered rating scales in clinical trials. He authored computer-administered versions of several clinician-administered rating scales, including depression and anxiety scales that are widely used today, and a computer-administered version of the PRIME-MD, a diagnostic interview that was published in JAMA.
Kobak received several NIMH grants to develop and study rater training methodology for depression, schizophrenia, and autism.
Negash serves as the scientific lead bridging research and operations to ensure MedAvante-ProPhase clinical trial services are implemented successfully from a scientific and service delivery perspective.
Her work has focused on investigating factors associated with successful cognitive aging, including lifestyle factors such as cognitive activity, and on developing interventions that enhance cognitive fitness in older adults. She also studies successful cognitive aging in minority populations, particularly African-Americans. Her other area of work focuses on examining implicit and explicit learning and memory systems in healthy aging and in mild cognitive impairment.
Kane has been the principal investigator for research projects focusing on schizophrenia, psychobiolgy and treatment, recovery, and improving quality and cost of care. He is the author of over peer-reviewed papers and serves on the editorial boards of numerous journals. Sue Vallow is a patient-reported outcomes PRO scientist with more than 20 years of experience developing and implementing patient-focused outcomes strategies and capabilities in numerous therapeutic areas with a specialty in CNS trials.
She is a co-author of more than 20 peer-reviewed papers and more than 70 research posters and presentations. Sofija Jovic is focused on the strategic combination of MedAvante-ProPhase as the thought leader in using measurement science and data quality to transform clinical trials. Jovic guided the transformation from a four-person start-up to a global industry leader in collaboration with ProPhase founder Dr. Jovic started her career as a clinical psychologist: Jovic has published in peer-reviewed journals and presented scientific papers at professional and industry conferences.